Analyses

In this section:

MS-based analysis of protein interactions and aggregations

With High-Mass MALDI-TOF MS, you can study protein interactions more rapidly, more cost effectively and more accurately. PANATecs uses this innovative technique developed by CovalX.

Characterisation of protein complexes

           •     Mass determination and stoichiometry

                  of non-covalent protein complexes

           •     Identification of complex components

           •     Label- and immobilisation-free detection

                   of covalently stabilised complexes

Characterisation of therapeutic protein aggregates

           •     Elucidation of aggregates during manufacture,

                  formulation and storage

           •     Detection of protein multimers

                  (up to 1.5 MDa) 

Antibody characterisation in therapy and diagnostics

           •     Antigen-Antibody interaction analysis

           •     ELISA optimisation

           •     Surface Plasmon Resonance (SPR) optimisation

           •     Epitope mapping

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